Education and Career
After finishing high school in 1964, I did my undergraduate studies in chemistry at the University of Amsterdam, the Netherlands finishing with majors in synthetic organic chemistry and chemical engineering in 1971.
I started graduate studies in synthetic organic chemistry in 1972 finishing with a PhD in 1977.
I was a NATO Science Fellow post-doc at the State University of Ghent, Belgium in 1977 through February 1998. From March 1978 until August 1979, I joined the Laboratory of Analytical Chemistry at the University of Amsterdam with Prof. Hans Poppe and became deeply involved in analytical chemistry and in particular in HPLC.
I joined the Waldbronn Analytical Division of Hewlett-Packard in Germany on September 1, 1979 as an R&D chemist. My first projects was the synthesis of proprietary stationary phases for HPLC. Soon however, I became involved in the development of the HP1090 and in particular the packing of 100x2.1 mm i.d. HPLC columns and test of the complete system for performance, reliability, usability and new applications of what became known as "Low Dispersion Liquid Chromatography". The HP1090 was introduced in 1983. In the same year I became an R&D section manager.
My focus has been on system performance evauation, applications, solutions, and HPLC column development. E.g. my group has exploited the abilities of the HP1090 to execute on-line sample derivatization which led to the AminoQuant system for analysis of proteinaceous and physiological amino acids. Later I was involved in the the development of an automated system for the analysis of polar pollutants in surface water like the Rhine river (SAMOS).
HPLC system evaluation became a permanent focal point e.g. during development of HP1050 and HP1100 series of HPLC modules and systems. My group was also involved in the development of the HP1046 fluorescence and HP1049 electrochemical detector for HPLC.
In 1986-1987 I became deeply involved in the joint venture of Hewlett-Packard and Genentech named HP Genenchem which had been established in 1983. I was an R&D section manager and was responsible for instrument and column development and spend several months in California at the premises of Genentech. Eventually an offering of OEM HPLC column products for biomolecules and a titanium version of the 1050 series of HPLC modules have come out of this endeavor. The HP Genenchem joint venture was dissolved in 1987.
In returning to Germany HPLC column development Hewlett-Packard had moved away from the idea to build HPLC stationary phases from scratch and focused on rebranding phases from other suppliers like Shandon (now Hypersil), E. Merck and Asahi. I was responsible for developing the packing processes and their transfer into manufacturing. Eventually capillary columns with i.d. 0.3 and 0.5 mm were introduced. I was also involved in the acquisition of Rockland Technologies Inc. (Zorbax product line) by Hewlett-Packard in 1998.
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